A mission of the CGA is to offer a forum for collaborative research. The reference and abstract of publications that have come from group collaboration are listed below. Full text articles may be accessed by linking to www.pubmed.gov
Church J1, Berk T2, Boman BM3, Guillem J4, Lynch C,5 Lynch P6, Rodriguez-Bigas M6, Rusin L7, Weber T8. Staging Intra-Abdominal Desmoid Tumors in Familial Adenomatous Polyposis: A Search for a Uniform Approach to a Troubling Disease. Dis Colon Rectum 2005; 48: 1528-1534.
Authors' Institutions:
1.Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland OH
2.Familial Cancer Registry, Mt. Sinai Hospital, Toronto, Ontario, Canada
3.Jefferson Hereditary Cancer Center, Philadelphia PA
4.Solan Kettering Cancer Center, New York NY
5.St. Vincent Hospital, Fitzroy, Victoria, Australia
6.MD Anderson Cancer Center, University of Texas, Houston TX
7.Department of Colon and Rectal Surgery, Lahey Clinic, Burlington MA
8.New York Metro Familial Cancer Registry, Albert Einstein College of Medicine, New York NY
Abstract:
INTRODUCTION: Desmoid tumors are a clinical problem in 12 to 15 percent of patients with familial adenomatous polyposis. There is no predictably effective treatment for intra-abdominal desmoid tumors, which sometimes cause significant complications by their effects on the ureters or bowel. The relative rarity and the clinical heterogeneity of intra-abdominal desmoid tumors make randomized studies difficult to do. In this article a staging system is proposed to make multi-institutional studies easier. METHODS: Intra-abdominal desmoid tumors can be staged according to their size, clinical presentations, and growth pattern. CONCLUSION: A way of staging intra-abdominal desmoid tumors is proposed to facilitate stratification by disease severity during collaborative studies of various treatments. (Key words: Desmoid tumor; Familial adenomatous polyposis; Staging)
Church J, Simmang C. Standards Task Force; American Society of Colon and Rectal Surgeons; Collaborative Group of the Americas on Inherited Colorectal Cancer and the Standards Committee of the American Society of Colon and Rectal Surgeons. Practice parameters for the treatment of patients with dominantly inherited colorectal cancer. Dis Col Rectum 2003 Aug:46(8):1001-1012.
Church JM, Lowry A, Simmang C. Standards Task Force; American Society of Colon and Rectal Surgeons; Collaborative Group of the Americas on Inherited Colorectal Cancer and the Standards Committee of the American Society of Colon and Rectal Surgeons. Practice parameters for the identification and testing of patients at risk for dominantly inherited colorectal cancer. Dis Colon Rectum 2001 44(10):1404-1412.